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Computational Pangenomics: Algorithms & Applications

Date:

Friday, 4th September

Time:

17:00 to 20:00 (CEST)

Organisers

  • Solon P. Pissis | Centrum Wiskunde & Informatica (CWI), The Netherlands
  • Yuri Pirola | Università degli Studi di Milano-Bicocca (UNIMIB), Italy

Invited Speakers

  • Valentina Boeva | ETH Zürich, Switzerland
  • Tobias Marshall | Universität Düsseldorf, Germany

Summary

Computational Pangenomics encompasses different research efforts for transitioning the existing paradigm from a sequence-based reference genome to a pan-genome, i.e., an evolutionarily coherent collections of genomes. Such a transition is urgently needed to effectively exploit the data masses produced by the technical advances and the widespread adoption of sequencing technologies. Graph-based representations of collections of genomes and diploid-aware assemblers have been recently proposed, but a large amount of work is still needed to shift to a pan-genomic view into the current research practice.

Computational Pangenomics is at its infancy and, to better sustain its full (and possibly, rapid) development, an interdisciplinary collaboration between Bioinformatics, Theoretical Computer Science, and Medicine is of crucial importance. As such, the workshop aims to provide an occasion for researchers of these disciplines to know the recent advances of the topic and the questions that will drive the future research efforts in this area.

This virtual workshop is articulated in two keynote talks focusing on algorithms (graph and string algorithms, indexing) and on applications (genome assembly, variant calling, comparative and evolutionary genomics) and in several invited talks given by researchers from the EU Project PANGAIA’s partners.

Target audience

The workshop aims to strengthen the interdisciplinary collaborations between computer scientists and bioinformaticians as well as practitioners of the field of computational genomics that are interested to deal with the complexity of data related to genomes at population scale.

The workshop is open to everyone who wants to share their ideas and work about algorithms and applications related to computational pangenomics.

Furthermore, the workshop is the main occasion to present the EU Project PANGAIA (https://www.pangenome.eu/)  to  the  whole  community  of  researchers  in  computational biology. Participants will be able to virtually meet the members and the partners of the PANGAIA project and, possibly, start new collaborations on the subject.

Schedule

Time (CEST)
Details
17:00 - 17:45 Tobias Marshall
17:45 - 18:30 Valentina Boeva
18:30 - 19:30 Invited talks given by researchers from the EU Project
PANGAIA’s partners
19:30 - 20:00 Final round table with the keynote and invited speakers